295: Are cervicovaginal fluid inflammatory mediators associated with mid-trimester cervical shortening in women with prior spontaneous preterm birth?
نویسندگان
چکیده
منابع مشابه
Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women
RESEARCH QUESTION Preterm birth (PTB) is the leading cause of perinatal mortality worldwide, with the greatest burden occurring in resource-constrained settings. Based on the hypothesis that altered placental angiogenesis and inflammation early in pregnancy lead to PTB, we examined whether levels of inflammatory and angiogenic mediators, measured early in pregnancy, were predictive of spontaneo...
متن کاملLimited Relationship between Cervico-Vaginal Fluid Cytokine Profiles and Cervical Shortening in Women at High Risk of Spontaneous Preterm Birth
OBJECTIVE To determine the relationship between high vaginal pro-inflammatory cytokines and cervical shortening in women at high risk of spontaneous preterm labor and to assess the influence of cervical cerclage and vaginal progesterone on this relationship. METHODS This prospective longitudinal observational study assessed 112 women with at least one previous preterm delivery between 16 and ...
متن کاملMid-trimester amniotic fluid pro-inflammatory biomarkers and the risk of spontaneous preterm delivery
Methods We performed a case-control study nested in a large prospective cohort of asymptomatic pregnant women that underwent mid-trimester genetic amniocentesis between 15 and 23 weeks. Twenty-one women who subsequently delivered spontaneously before 35 weeks of gestation (cases) were paired with twenty-one women who delivered at term (controls). Magnetic bead-based multiplex immunoassays were ...
متن کاملMid-Trimester Cervical Consistency Index and Cervical Length to Predict Spontaneous Preterm Birth in a High-Risk Population
Background Short cervical length (CL) has not been shown to be adequate as a single predictor of spontaneous preterm birth (sPTB) in high-risk pregnancies. Objective The objective of this study was to evaluate the performance of the mid-trimester cervical consistency index (CCI) to predict sPTB in a cohort of high-risk pregnancies and to compare the results with those obtained with the CL. St...
متن کاملCervical Sonoelastography and Cervical Length Measurement but not Cervicovaginal Interleukin-6 Are Predictors for Preterm Birth.
Worldwide, preterm birth annually affects more than 15 million infants. Despite increasing knowledge of the risk factors and mechanisms associated with preterm labor, the preterm birth rate has risen in most industrialized countries. The ability to identify women at high risk for spontaneous preterm birth is crucial yet remains difficult. The aim of the present study was to assess the value of ...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2017
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2016.11.553